doi: 10.1146/annurev-ento-120811-153650 Anangi, Raveendra, Koshy, Shyny, Huq, Redwan, Beeton, Christine, Chuang, Woei-Jer and King, Glenn F
Brazeau P, Vale W, Burgus R, Ling N, Butcher M, Rivier J, et al
By stimulating collagen synthesis and reorganizing damaged tissue fibers, the skin begins to appear plumper, more supple, and younger over time
Altman and P
Amphetamines disrupt VMAT2 function and vesicular uptake through a combination of mechanisms: The Weak Base Effect (pH Gradient Collapse) : Amphetamines are lipophilic weak bases (pKa of 9.9) that can readily diffuse across both the plasma and vesicular membranes to accumulate inside synaptic vesicles (Wimalasena 2011)
However, high-dose oral therapy (1,0002,000 g daily) may be effective in some cases through passive diffusion, with appropriate monitoring